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A melanocortin receptor agonist, -MSH is synthesized in the pituitary gland of most vertebrates, and is responsible for regulating energy balance [1]

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A lower 4mg weekly dose also resulted in impressive weight loss results, with an average loss of 17% over 48 weeks and: 92% of participants lost at least 5% of their starting body weight 75% lost at least 10% of their body weight 60% lost at least 15% of their starting weight Retatrutide vs Mounjaro In clinical trials, the active ingredient in Mounjaro, tirzepatide, results in an average weight loss of 22.5% at the highest 15mg per week dose over 72 weeks

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Compounding pharmacies create these formulations as an alternative to brand-name products like Ozempic and Wegovy