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Each dose of GHK-Cu contains a very small amount of copper relative to dietary intake

Lott IT, Doran E, Nguyen VQ, Tournay A, Head E, Gillen DL (2011) Down Syndrome and Dementia: A Randomized, Controlled Trial of Antioxidant Supplementation

Anyone on medications should discuss potential interactions before use

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Avoid simultaneous use with strong acids or chelators (e.g., vitamin C or retinol serums) because they can inactivate copper peptides

Dialysis may be required temporarily (renal recovery generally occurs eventually if the patient survives)