Less common side effects may include headache, dizziness, and allergic reactions such as rash or pruritus
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
(Boston, MA: Springer), 719722
Persistent white patches can be due to leucoplakia , which is associated with alcohol and (particularly) smoking, and is premalignant
Several mid-stage trials will read out in 2025 to provide important proof points for novel MoAs and their potential for differentiation, e.g., Lillys bimagrumab (activin/myostatin type II receptor inhibitor) in combination with semaglutide, aiming to deliver weight loss while preserving muscle mass (phase 2b)
Dietary supplements should be used as part of a healthy lifestyle and not as a substitute for a varied and balanced diet