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It wasnt until September 2023 that the FDA required a warning for ileus and intestinal blockage for these drugs

Therefore, breastfeeding is generally not advised while receiving sermorelin, or the drug should be used only if clearly needed and if the mothers healthcare provider determines that the benefits outweigh the potential risks to the infant

Patient education materials should clearly outline these storage guidelines to prevent medication waste and ensure therapeutic effectiveness

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4144 Moreover, it has been shown that GLP-1RAs also promote satiety trough the activation of the nucleus accumbens by increasing glutamatergic signaling, thus suppressing feeding behavior