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Bottom line: For men, glutathione acts as a primary defense against DNA damage in sperm, which is essential for successful fertilization and healthy pregnancy outcomes

Many semaglutide formulations now include B12 , and tirzepatide with B12 is similarly available

Instruct patients using ZEPBOUND vials to always use a new syringe and needle for each injection

Extended Data Figure 5 ECL3, TM7, TM1 and ICL3 may be associated with GLP-1R biased agonism

For travelers using compounded medication, our article on compounded semaglutide storage, travel, and handling covers the same temperature concerns in more detail