Discussion In this article, we reviewed pre-clinical and mechanistic studies (in vitro, in animal and in human) and clinical studies, leveraging potential translational aspects, on GLP-1RAs across a variety of cognitive and mental health disorders
The current evidence indicates promising potential, however a broader validation is required, specifically in the context of PsA
Oral Wegovy (Semaglutide Pill) Approved by the FDA in December 2025, this daily pill offers the same GLP-1 weight loss benefits as its injectable counterpart
Postgrad Med 134(1):1419
Studies show an age-adjusted incidence of 2.4 per 100,000 person-years for males and 9.8 for females [4]
Expression of the GIP receptor appears to be more ubiquitous, with Protein Atlas (proteinatlas.org