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Eye Effects: Cataracts and Glaucoma There is some evidence that long-term corticosteroid use can increase the risk of cataracts and glaucoma, although this is more common with oral or injected steroids

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It is important to remember most people with obesity generally have two to three comorbid conditions, if not more, Rubino said

Conditions, such as pregnancy, in which estradiol levels are high, are a high-risk time where susceptible women are more at risk of developing metabolic comorbidities such as obesity and gestational diabetes

Feel for the softness of subcutaneous fat versus the firmness of underlying muscle

With that baseline, its easier to see why GLP-1 users might notice changes