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The Authors reported that treatment with incretins significantly suppressed the FSH-induced synthesis of progesterone through the inhibition of the expression of progestogenic factors and enzymes, whereas there was no significant effect on oestrogen synthesis by rat granulosa cells, thus suggesting the possible role of GLP-1 RA in the treatment of dysregulated steroidogenesis in PCOS [43]

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Signs of vascular dysfunction were completely prevented by benfotiamine administration, and biomarkers of endothelial dysfunction and oxidative stress were significantly reduced (Stirban 2006)

Together, these findings highlight the complex and context-specific role of complex I in ferroptosis regulation

Due to its defined molecular structure and stable analytical profile, PT-141 is frequently referenced in experimental peptide research models