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Activated astrocytes produce various proteoglycans, such as neurocan, phosphacan, and keratan-sulfate ( FIGURE 5 The process of scar formation probably exerts a role in protecting the integrity of the blood brain barrier (BBB) and in avoiding further cellular degeneration

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A serum folate of 3 g/L or lower indicates deficiency

| Target Concentration | BAC Water to Add | Dose per 10 units on syringe | |---------------------|-----------------|------------------------------| | 10mg/ml | 3.0ml | 1.0mg | | 15mg/ml | 2.0ml | 1.5mg | | 6mg/ml | 5.0ml | 0.6mg | **Best for:** Patients on 4-12mg weekly doses who want the best cost-per-milligram value