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Almost all patients report a much greater degree of comfort immediately after their procedure

During the opening lecture at the International Conference on Advanced Technologies & Treatments for Diabetes, Melanie Davies, CBE, MB, ChB, MD, FRCP, FRCGP, professor of diabetes medicine at the University of Leicester and an honorary consultant diabetologist at the University Hospitals of Leicester NHS Trust, reviewed how GLP-1 receptor agonists such as semaglutide (Ozempic/Wegovy, Novo Nordisk) have changed the way providers approach the treatment of type 2 diabetes and obesity and discussed some of the medications that combine GLP-1 with other molecules

While the report did not delve into why patients quit, it does offer a sobering view of the real-world experiences of people taking the drugs

As I mentioned earlier, losing substantial weight doesnt consistently correlate with fibromyalgia improvement, and some people report their symptoms worsening as they lose weight, which is consistent with what we know about how muscle loss affects joint stability and pain in hypermobility

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Its much less potent than GLP-1s, but the muscle-sparing effect is important, as one-third of the weight lost on GLP-1s is muscle mass