The Abbreviated New Drug Application (ANDA) process for a complex peptide like semaglutide requires demonstrating bioequivalence through pharmacokinetic studies, which can't be started until the manufacturer is confident they won't face patent litigation
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The pGBKT7-53/pGADT7-T interaction served as a positive control, while the pGBKT7-Lam/pGADT7-T served as a negative control