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However, the proportion of adult born neurons originating from birth-dated HIF1a +/ NSCs was unaffected by IH EARLY

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FIGURE 3 The pharmacokinetic (PK) profile of GL is highly dependent on the route of administration, with marked differences between oral and intravenous delivery due to its unique metabolic pathways and transporter-mediated disposition

Conventional Skin Whitening Treatments Topical Therapies Hydroquinone: Blocks the production of melanin by inhibiting tyrosinase Retinoids: Stimulate cell turnover and inhibit melanin transfer Kojic Acid: Fungus-derived, suppresses melanin development Vitamin C: An Antioxidant that interferes with melanin production and whitens skin Alpha-Arbutin: Plant extract that minimises melanin production Azelaic Acid: Minimizes inflammation and hyperpigmentation Professional Treatments Chemical Peels: Ablate surface skin to diminish pigmentation Microdermabrasion: Exfoliates surface skin with exposure to reveal brighter underlying layers Laser Procedures: Tackle melanin deposits using highly concentrated light Intense Pulsed Light (IPL): Type similar to laser, but has a number of different wavelengths Glutathione Injections: Intravenous antioxidant injections (shady practice) Cryosurgery: Destroys dark spots by freezing them off Skin Whitening Laser Treatment Cost The cost of laser skin whitening treatments differs widely depending on location, clinic reputation, technology used, and the treated area: In India: Urban cities (Delhi, Mumbai, Bangalore): 5,000-25,000 per session Tier II cities: 3,000-15,000 per session High-end dermatology clinics: 10,000-30,000 per session Package offers: 25,000-100,000 for several sessions At Punes Homeo Care Clinic , Dr

Presented for research literature review only Li P et al

PubMed Urva, S., Coskun, T., Loghin, C., Cui, X., Beebe, E., OFarrell, L., et al