It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
Hirafuji M et al
Oral delivery via PepT1: Published research (Dalmasso et al., 2008, Gastroenterology ) demonstrated that KPV can be absorbed through the PepT1 intestinal peptide transporter, enabling oral administration extremely unusual for a therapeutic peptide
Order confidence TB-500 + BPC-157 Reference Set is listed for qualified in-vitro laboratory research only
ClinicalTrials.gov identifier: NCT04074161