Int J Cardiol 292:218224 Dunning BE, Foley JE, Ahrn B (2005) Alpha cell function in health and disease: influence of glucagon-like peptide-1
22 The current proof-of-concept study was designed to evaluate whether (in)GSH is capable of augmenting CNS GSH concentrations, as measured by 1 H-MRS
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This mechanistic difference has a real implication: CagriSema primarily works by reducing energy intake (dual satiety signals), while retatrutide works by both reducing energy intake and increasing energy expenditure (appetite suppression plus thermogenesis)
The study was funded by WW International
And thats over 15% of their body weight and went along with impressive metabolic health benefits