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ClinicalTrials.gov lists ongoing studies
The molecule carries an -aminoisobutyric acid (Aib) substitution at position 2 that blocks DPP-IV cleavage, conferring complete resistance to the proteolytic step that inactivates native incretins within minutes
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GHRH analogues (CJC-1295/Sermorelin) aim to restore pituitary control and physiological secretion
These studies were conducted to validate the amazing success of this drug
The reduction in sweet cravings is particularly valuable because sugar and processed carbohydrate consumption drives insulin-mediated hunger cycles that can perpetuate overeating independent of actual energy needs
