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1 Introduction Ensuring food security is a real problem, given climate change and the rapid increase in food demand for an ever-growing population estimated to be around 10.4 billion by 2100 (Adam, 2022)

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As such, SKO mice provide a valuable model to examine potential therapies for lipodystrophies

People whose BMI is 40.0 or greater are sometimes categorized as severely obese. The CDC has more information about BMI, its uses and how to calculate it

Pharmacol Res 85, 2332 (2014)

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