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TB-500 (Thymosin Beta-4 Fragment) is a synthetic 43-amino acid peptide derived from the naturally occurring thymosin beta-4 protein, one of the most abundant intracellular proteins in mammalian cells

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This prevents transcription of pro-inflammatory cytokines including TNF-, IL-6, and IL-1operating upstream of enzymatic pathways targeted by NSAIDs or corticosteroids

While oral bioavailability may be lower compared to injections, it offers systemic benefits and convenience

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