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The most commonly reported adverse reactions in clinical trials were gastrointestinal: nausea (up to 18 to 24% of users), diarrhea (up to 17%), vomiting, constipation, decreased appetite, dyspepsia, and abdominal pain
It is caused by the interplay between endothelial cells, vascular smooth muscle and macrophages
Theyre also really helpful for fibroids and cysts
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There were also no changes in exposure over time (up to 104 weeks) or relevant exposure differences in subjects with antibody development
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