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There are two primary melanins: eumelanin, which gives darker tones, and pheomelanin, which causes lighter skin

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The ER-mitochondria tethering complex VAPB-PTPIP51 regulates autophagy

Patients were stratified by SGLT2i and GLP-1 RA prescriptions at their index hospitalization, with a time-varying KaplanMeier approach accounting for treatment changes if additional prescriptions were initiated post-index

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Repeated straining over time can cause the supporting tissues to stretch and weaken, potentially leading to hemorrhoid formation or prolapse of existing hemorrhoids