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The Nutritional Gap Challenge A 2025 study published in ScienceDirect found that over 20% of people starting GLP-1 therapy had nutritional deficiencies diagnosed within the first year
The data is not that neat
Lee, J.D., Nunes, E.V., Novo, P., et al
P-CTX (procollagen type I C-terminal cross-linked telopeptide), a marker of bone resorption, increased significantly in the semaglutide group compared to placebo (p = 0.021)
Tan TM, Field BC, McCullough KA, Troke RC, Chambers ES, Salem V, et al
FIGURE 2 3.3 Hypoxic-glucose deprivation conditions can induce senescence in endothelial cells Unlike the previously mentioned natural aging models and progeria models, there is another common but often overlooked endothelial cell aging model: hypoxia-induced endothelial cell senescence
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