However, it did not work well in IDH1 mutant tumors
This buildup causes muscle soreness and cramps & makes you feel weak after an intense workout
Second, by supporting overall energy production from fat stores, it may help reduce the fatigue and low energy that many people experience during rapid weight loss on GLP-1 medications
Clinical impact: Associated with higher risk of hypertension, coronary artery disease, and stroke
Maiti A, DiNardo CD, Rausch CR, Cortes JE, Pemmaraju N, Daver NG, Ravandi F, Garcia-Manero G, Borthakur GM, Naqvi K, Ohanian MN, Short NJ, Alvarado Y, Benton CB, Kadia TM, Takahashi K, Yilmaz ME, MD, Jain N, Kornblau SM, Sasaki K, Andreeff M , Bose P, Ferrajoli A, Issa GC, Jabbour E, Masarova L, Rytting ME, Thompson PA, Wang SA, Konoplev S, Chen Z, Goswami M, Maduike R, Guerrero JA, Zhang Q, Cavazos A, Ma H, Bivins CA, Wade A, Adewale SL, Tse S, Thomas R, Vaughan K, Pierce SA, Ning J, Qiao W, Welch JS, Kantarjian HM, Konopleva MY
Educating patients on side effect timelines and titration schedules can enhance tolerance