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Although the majority of patients have mild symptoms, for some patients, symptoms of dumping syndrome can be debilitating and emotionally distressing, and are associated with a significant reduction in quality of life

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But half-life and duration of effect are different things

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For researchers replicating the SURMOUNT 4-week step escalation (2.5 5 7.5 10 12.5 15 mg, 4 weeks at each step), a 15mg vial used at 10mg/mL working concentration supports the first two escalation steps (8 weeks of 2.5mg + 5mg doses from one vial) before larger formats become economical