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Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)
Premedication was administered using 3 mg/kg of xylazine, followed by general anesthesia with 50 mg/kg of ketamine
It is essential for the formation of collagen that helps support connective tissues like skin, bone, cartilage, and tendons
The included studies that applied EX indicated no changes in CCK, while CR-induced weight loss led to a decrease in CCK
10.26773/mjssm.210901 48
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