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Dulaglutide and Cardiovascular Outcomes in Type 2 Diabetes (REWIND): A Double-Blind, Randomised Placebo-Controlled Trial
(Hoboken, NJ: John Wiley & Sons) 7083
When used for weight management, they are recommended for those with a body mass index (BMI) of 30 and higher or a BMI of 27 and higher in individuals with a weight-related health condition, such as high blood pressure
This suggests inhibition of vagal cholinergic input into the stomach with a concomitant increase in gastric volume, though the exact mechanism is not clear
One of the primary areas of scientific interest involves melanocortin receptor biology
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