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The peptide distributes through the bloodstream from there, reaching target tissues via standard circulatory pathways
However, that historical origin should not be interpreted as proof that all reported effects share the same mechanism or the same biological relevance
The GLP GT-1 served this purpose well, as it is lighter than its cousins and a bit smaller
Starting at a low dose and gradually increasing (a process called titration) helps minimize side effects
Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype
Similarly, Liebmann et al
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