tirzepatide improved mood Semaglutide/Tirzepatide: Beyond Weight Loss: Shamsah Amersi, MD: OB-GYNs Tirzepatide & Depression: Evidence &

10.1021/acschembio.7b00730 115 ShahR.ShchepinovM

What the SELECT trial actually showed The SELECT trial, published in The New England Journal of Medicine in 2023, was a large randomized, placebo-controlled cardiovascular outcomes trial

With benefits extending beyond weight loss, tirzepatide helps in maintaining metabolic health, reducing cravings, and enhancing overall energy and mobility

Last month, Max Marchione, the 25-year-old Australian founder of $300 million San Francisco health technology start-up Superpower squared off in a live YouTube debate with Martin Shkreli, the notorious pharma bro who spent five years in prison for securities fraud

A prominent and potentially life-threatening health risk of taking IGF-1 LR3 is hypoglycemia

Like other incretin-based medications, the most common side effects were gastrointestinal: Common Side Effects Nausea: Reported in approximately 25-45% of participants depending on dose (most common during titration) Diarrhea: Approximately 20-35% of participants Vomiting: Approximately 10-20% of participants Constipation: Approximately 10-15% of participants Decreased appetite: Common and expected given the mechanism of action Less Common but Notable Effects Increased heart rate: Small elevations in resting heart rate were observed, consistent with other GLP-1 class medications Injection site reactions: Mild redness or itching at injection sites Fatigue: Reported by some participants, particularly during dose escalation Most adverse events were mild to moderate and occurred primarily during the dose escalation phase