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Patient safety advice should include: Reporting severe or persistent abdominal pain immediately Maintaining adequate hydration, particularly during gastrointestinal upset Monitoring for signs of depression or suicidal ideation (regulatory authorities are monitoring this signal, though no causal link has been established) Understanding that rapid weight loss may necessitate adjustment of other medications Regarding pregnancy , advice is product-specific: Wegovy and Saxenda are contraindicated in pregnancy

El cepillado de la lengua puede ocasionar una regresin parcial de la lesin

Loss of Skin Elasticity As fat volume reduces, skin elasticity may not keep up, especially in patients over 35

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2.2 Recommendations for Use in Renal Impairment Assess renal function prior to initiation of JANUMET XR and periodically thereafter

This combination minimizes pain and bruising while ensuring proper subcutaneous delivery