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30 Additionally, researchers have reported activation of microglia and changes to subcortical white matter, loss of oligodendrocytes, loss of oligodendrocyte precursor cells and myelin 31,32 (Figure 1)
Atherosclerosis 325 , 815 (2021)
5-Amino-1MQ works by inhibiting NNMT (nicotinamide N-methyltransferase), an enzyme that depletes cellular NAD+ and SAM
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