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One positive note: tirzepatide has actually shown renal protective effects in some studies, particularly in patients with type 2 diabetes

The following CVOTs, relative to DPP-4i and GLP-1RAs, have been identified and included in this review: EXAMINE, SAVOR-TIMI53, TECOS, CARMELINA, CAROLINA, ELIXA, SUSTAIN 6, EXSCEL, HARMONY, LEADER, PIONEER 6, REWIND, and AMPLITUDE-O [47,48,49, 53, 54, 56,57,58,59,60,61,62,63]

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The formula looks like this: units equals parenthesis desired dose in mg divided by concentration in mg per mL close parenthesis times 100