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Stratospheric ozone and its importance
A thorough research analysis revealed that the Western diet exacerbated PD progression due to the poor quality of fiber, whereas the Mediterranean diet, high in fiber and polyphenols alleviated the symptoms of PD (142)
Notably, increased NAD+ levels also activate NAD+dependent signaling pathways such as sirtuins (SIRT1/SIRT3), further enhancing mitochondrial biogenesis and energy metabolism
Narrow margin between therapeutic dose and toxic dose
Gourbal B, Pinaud S, Beckers GJM, Van Der Meer JWM, Conrath U, Netea MG (2018) Innate immune memory: an evolutionary perspective
