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It is FDA-approved to manage type 2 diabetes and reduce cardiovascular risks in people with diabetes and heart disease
Initially described as a mediator of exercise-induced browning of white adipose tissue and increased energy expenditure, irisin was proposed as a candidate exercise- associated signaling molecule ( Subsequent debate regarding assay specificity, circulating concentrations, and translational relevance led to skepticism regarding irisins role in humans
Chronic infusion of MG induces type 2 diabetes and MG is considered as a possible mediator of hyperglycemia-induced type 2 diabetes 5
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But did you know that the heart is a muscle as well
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