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Additionally, anyone taking certain diabetes medications (sulfonylureas, insulin) faces increased hypoglycemia risk when combining these drugs with GLP-1 agents, necessitating dose reductions supervised by qualified physicians
The active compounds are olive oil polyphenols -- specifically hydroxytyrosol, oleocanthal, oleuropein, and elenolic acid
Mechanistically, these effects are linked to GLP-1 RA-mediated suppression of inflammatory pathways, modulation of skeletal muscle metabolism, and preservation of mitochondrial function, thereby influencing insulin resistance
J.GrunbergerG.et al (2009)
How does DPP-4 enzyme affect GLP-1 signaling
Your physician should also assess for contraindications, including personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or history of severe gastrointestinal disease
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