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AOD9604 acts directly on fat metabolism but doesnt meaningfully raise HGH or IGF1 levels (human safety data)

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NAD+ metabolism enzyme NNMT in cancer-associated fibroblasts drives immune evasion in urothelial carcinoma by elevating PD-L1 N-glycosylation

Escalation typically proceeds: 2.5mg weeks 1-4, 5mg weeks 5-8, 7.5mg weeks 9-12, with potential increases to 10mg, 12.5mg, or 15mg

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