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Topical NSAIDs (such as ibuprofen gel) are recommended by NICE as first-line for localised joint pain

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doi:10.1016/j.molmet.2017.07.007 Bain SC, Mosenzon O, Arechavaleta R, et al

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Patients should be encouraged to consume a varied, nutrient-dense diet rich in: Iron found in red meat, poultry, fish, lentils, and fortified cereals Zinc present in shellfish, meat, seeds, and nuts Vitamin D obtained through sunlight exposure, oily fish, and fortified foods B vitamins , particularly B12 found in animal products and fortified alternatives For patients struggling to meet nutritional requirements through diet alone, a standard multivitamin supplement within recommended daily allowance (RDA) limits may be considered after discussion with a healthcare professional

GLP-1 receptor agonist 12 can be used in the study of diseases such as diabetes [1]