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According to clinical trials published in the New England Journal of Medicine, Zepbound shows slightly higher rates of GI effects at higher doses: nausea (31-33%), diarrhea (21-23%), and vomiting (12-20%)
Why would the body have GLP-1 receptors on our peripheral organs, if the hormone acts mainly through the vagus nerve
Owing to the progressive nature of the disease, most patients ultimately require a combination of pharmacological therapies to achieve glycaemic control [1,2,3]
These include cases where metformin is ineffective, contraindicated, or when a clients A1C remains above target levels despite three months of treatment if they also have conditions like atherosclerosis, heart failure, or chronic kidney disease (6)(16)
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