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Most clinical trials employed gradual dose titration protocols specifically to minimize gastrointestinal side effects, with discontinuation rates due to GI adverse events ranging from 47% in the STEP trials
Frequent exposure of the esophagus to stomach acid can cause esophagitis, an inflammation of the esophagus that can lead to pain, ulcers, and difficulty swallowing
He ate dinner then laid on the couch to watch TV
Protein intake is particularly important, with 1.01.2 grams per kilogram body weight daily recommended to preserve lean muscle mass