Specifically, GLP-1 receptor activation decreased anticipatory food reward responses in the OFC, putamen, left insula, and left amygdala, while it increased consummatory reward responses in the right OFC, putamen, left insula, left amygdala, and right caudate (van Bloemendaal et al., 2015a)

Lifestyle & Nutrition Guidelines Dietary Support Whole-Food, Balanced Diet: Supports hormone function and recovery Protein-Rich Foods: Essential for muscle repair and overall wellness Hydration: Aim for 64+ oz of water daily to maintain optimal function Exercise Recommendations Strength Training: 35x per week to maximize muscle-building effects Daily Movement: Light activity such as walking or stretching for recovery High-Intensity Workouts: Beneficial for fat metabolism and overall fitness Sleep & Stress Management 79 Hours of Quality Sleep: Most effective when paired with deep, restorative sleep Minimize Stress: Supports balanced hormone levels and overall well-being Potential Side Effects & Management Injection Site Irritation: Rotate injection sites to prevent discomfort Water Retention: Maintain hydration and monitor sodium intake Nausea: Take the injection on an empty stomach or before bed to minimize symptoms Fatigue: Ensure adequate sleep and proper nutrition Headaches: Reduce dosage if necessary and increase electrolytes Most side effects are mild and temporary

Youll kick off your Metabolic Reset with lab work and a Comprehensive Health Intake, a few reading lessons from your Calibrate curriculum, a 1:1 video visit with your Calibrate coach to discuss your goals, and then a 20-minute, 1:1 video appointment with your Calibrate clinician
Monitor Progress Regular monitoring of your weight and dietary habits can help you stay on track
It is because your body has lost its adaptation to the GI-slowing effects, and jumping back to a full dose will likely cause the same nausea you experienced at the start
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