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2 Glutamine Metabolism in cancer Cells Glutamine is an important nitrogen resource for synthesizing amino acids and nucleotides and an important carbon source in the TCA cycle and lipid biosynthesis pathway (Figure 1) (Zhang et al., 2017
Although some spontaneous reactions could occur, the cytosolic glutathione transferases (GST) catalyze the nucleophilic conjugation of GSH with a wide spectrum of electrophiles (Hamada et al., 1994
refrigeration at 4 C (39 F) is acceptable for short-term storage (days to weeks)
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