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He previously participated in an adolescent weight management clinic where he engaged in intensive health behavior and lifestyle treatment for 6 months but experienced no significant weight change
I definitely think GLP-1 agonists have a significant role to play in diabetes management and overall agree with the ADA guidelines given the alternatives that cause hypoglycemia and weight gain, but I tend to feel a little more conservative about the weight management role of these medications
The cardiovascular biology of glucagon-like peptide-1
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Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic -cell mass and function in a rodent model of type 2 diabetes
![Structures of (a) GLP-1, (b) GIP and (c) tirzepatide [19, 88, 90]](https://www.researchgate.net/publication/370926483/figure/fig4/AS:11431281185432337@1693619320519/Structures-of-a-GLP-1-b-GIP-and-c-tirzepatide-19-88-90-Amino-acids-are.png)
