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DSIP also has GABAergic activity but appears to modulate sleep architecture rather than simply sedating
Single domain antibodies targeting receptor binding pockets of nadA restrain adhesion of neisseria meningitidis to human brain microvascular endothelial cells
The gut microbiome also affects the immune system, with ALS patients showing increased Th17 immune cells and higher levels of IL-17, an inflammatory cytokine that may worsen the disease (Zang et al., 2023)
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