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Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma

Notably, the sensitivity of BRCA1-deficient breast cancer cells to PARP inhibitors can be increased by inhibiting GPX4, thereby providing a novel strategy to overcome drug resistance [75]

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However, different nanoscale systems have their own advantages and limitations: SLN-AST demonstrates a clear advantage in prolonging drug half-life, but its lipid components may affect lipid metabolism