Your prescription should connect to a documented medical condition, such as type 2 diabetes, obesity, insulin resistance, prediabetes, or overweight with a related condition
A licensed provider sets your maintenance dose and adjusts it with you
[27], headache days per month significantly improved with semaglutide or liraglutide: the median change at 6 months was 4 days in the GLP-1 group versus 0 days in the control group ( p = 0.02)
The reasoning behind this restriction ties back to concerns about cardiovascular effects and the potential for tolerance, where the drug becomes less effective over time as the body adapts to elevated norepinephrine levels
Empirical evidence also suggests that while GLP-1 therapies may be useful in treating impulsive/addictive behaviours such as alcoholism and binge eating disorder, these therapies may have adverse effects, such as nausea, vomiting, and diarrhoea
Funding This study was funded by Otsuka Pharmaceutical Development & Commercialization, Inc., Princeton, New Jersey.