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The Wegovy injection a once-weekly subcutaneous pen has been FDA-approved since 2021 and carries the most extensive clinical data

Redness, itching, and localized swelling can occur with either medication, and these reactions are more common when the injection reaches muscle tissue or when technique is inconsistent

This can interfere with how hunger cues, insulin signals, and reproductive hormones are coordinated over the cycle

This is not a life-threatening decrease in blood flow, but its bothersome and some cases causes fainting

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A 2025 scoping review by McGuire and colleagues (Curr Rev Musculoskelet Med) found no adequately powered randomised controlled trials for BPC-157 in musculoskeletal healing