Anti-Aging Alpha-lipoic acid (ALA) and R-lipoic acid (R-ALA) are widely used in anti-aging supplements due to their powerful antioxidant properties
Folkerts , J., Maurer, M., Stadhouders, R., Hendricks, R., Galli, S., Tam, S.-Y., Junt , T., van IJcken, W., de Bruijn, M., van den Berg, M., Blokhuis, B., Folkerts, G., & Redegeld, F
[5] Sustained NO Production - L-citrulline creates a longer-lasting elevation of plasma arginine levels compared to direct L-arginine supplementation, providing extended NO production benefits
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Systemic metabolic alterations and their relationship to neuropsychiatric symptomatology PAIS, including long COVID, as well as CFS and IMD, share the characteristic of systemic metabolic disturbances, which may be a sign of underlying multi-organ inflammation and exhaustion [31], and consequently may contribute to neuropsychiatric symptomatology, as many metabolites can cross the bloodbrain barrier (BBB) [30, 58] (e.g., short chain fatty acids (SCFAs) derived from the gut microbiota such as acetate [40], amino acids such as tryptophan [52] and also carnitine/acetylcarnitine can cross the BBB via transporters [59])
Similarly, Chee et al.[8] found that older adults experienced a 20% increase in fat oxidation and improved metabolic flexibility after 25 weeks of supplementation and exercise