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What they found: Favorable safety profile , no serious adverse events at doses up to 100 g/kg Preliminary efficacy signals positive The program stopped before Phase 3 for unknown commercial reasons (the program passed through several sponsor rotations and no one ultimately carried it through) Why it matters: These are the only published clinical data in humans that we have
PubMed Central, Yokoyama, Akira, et al
Lysine may help promote muscle growth and recovery by supporting protein synthesis and activating muscle repair cells
For CrossFit athletes dealing with systemic inflammation from chronic high-intensity training, this has a compounding benefit -- it does not just help the specific injury, it reduces the overall inflammatory load that slows recovery across the board
(Increase in growth hormone receptor expression in tendon fibroblasts)
The study used 20 mg/kg SC three times daily in mice
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