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next is the central catalytic core that contains a PLP molecule forming a Schiff base with Lys119
Endocr Rev 2009
A study experimented VC in combination with each of eribulin mesylate, tamoxifen, fulvestrant, and trastuzumab on a variety of breast cancer cell lines (MCF7, SK-BR3, MDA-MB-231, and breast epithelial cells MCF10A), have shown that high-dose VC with each of those anti-cancer drugs had decreased the cell viability of cancer cells more comprehensively than high-dose of VC or chemotherapy alone (90)
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