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Molecular docking The structures of the ligand lithocholate sulfate (PubChem CID: 122391354) and receptor PDGFA (PDB ID: 3MJK) were constructed using OpenBabel 3.1.1 and PyMOL 3.1.0, respectively

Increased cAMP upregulates protein kinase A (PKA) and exchange protein activated by cAMP, which leads to rapid increases in intracellular calcium and insulin exocytosis in a glucose-dependent manner [33]

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