Notably, the enantiomer D-carnitine may exert hepatotoxic effects (89), underscoring the critical importance of compound-specific safety evaluation and reinforcing that only the biologically active L-isomer should be considered for therapeutic use in MASLD
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Some of the medications will need adjustment in subsequent months
The authors concluded that intravenous BPC157 was welltolerated, but stressed that larger, longerterm trials are needed
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So the argument to be made is using the lowest GLP-1 dose possible to elicit gradual weight loss over time while optimizing diet, resistance exercise, etc