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It is important to keep the tablets in their original sealed blister pack until you are ready to take one
Presented for research literature review only Juillerat-Jeanneret L et al
NICE guideline NG28 for type 2 diabetes recommends GLP-1 therapy for patients with inadequate glycaemic control despite optimal management with other glucose-lowering medications, and particularly for those who would benefit from weight loss
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Where it works: Liver: Increases hepatic glucose production and fat oxidation (when carbs are low) Adipose tissue: Stimulates lipolysis (breakdown of stored fat into free fatty acids) Brown adipose tissue: Activates thermogenesis (heat production from burning fat) Muscle: May increase fat oxidation during exercise Weight loss contribution: The glucagon component appears to add an additional 2-3% weight loss beyond the GLP-1/GIP combination (24% vs 22% for tirzepatide)
Gao, X., et al., Efficacy and safety of semaglutide on weight loss in obese or overweight patients without diabetes: A systematic review and meta-analysis of randomized controlled trials
Timing and consistency matter more than format
