Some acrolein-resistant mutants showed reduced glutathione content, suggesting that additional mechanismsindependent of glutathione accumulationmay also confer acrolein resistance
Introduction to meta-analysis
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Smoking is also associated with higher homocysteine levels.[ref][ref][ref] Folate and B12 status: In general, higher folate and vitamin B12 levels are associated with lower homocysteine levels.[ref] This association holds true with aging.[ref] Amount of methionine in the diet: Methionine is an essential amino acid found in protein-rich foods
In light of this, in combination with the observed age sex interaction, we conducted a post hoc analysis excluding the three female participants in the Older group, which are of postmenopausal age based on reports by the WHO (53) and the NHS (54)

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